@article{ref1,
title="An adult case of generalized convulsions caused by the ingestion of Ginkgo biloba seeds with alcohol",
journal="Internal medicine",
year="2020",
author="Azuma, Fumika and Nokura, Kazuya and Kako, Tetsuharu and Kobayashi, Daisuke and Yoshimura, Teruki and Wada, Keiji",
volume="ePub",
number="ePub",
pages="ePub-ePub",
abstract="A 64-year-old woman developed symptoms of vomiting and tonic-clonic convulsions 9.5 h after eating 50 roasted Ginkgo biloba seeds with 100 g of alcohol. The intravenous administration of pyridoxal phosphate effectively improved the symptoms. Blood samples were collected and stored over 35 h. The assessment of 4'-O-methylpyridoxine and vitamin B6 vitamers indicated high levels of both, but the pyridoxal phosphate levels were low during the acute stage. These results suggest that 4'-O-methylpyridoxine inhibits the transformation of vitamin B6 analogues to the active form, pyridoxal phosphate. In our case, alcohol may have extended the period until ginkgo intoxication appeared.<p /> <p>Language: en</p>",
language="en",
issn="0918-2918",
doi="10.2169/internalmedicine.4196-19",
url="http://dx.doi.org/10.2169/internalmedicine.4196-19"
}