@article{ref1,
title="Impact of blunt chest trauma on outcome after traumatic brain injury- a matched-pair analysis of the TraumaRegister DGU®",
journal="Scandinavian journal of trauma, resuscitation and emergency medicine",
year="2020",
author="Schieren, Mark and Wappler, Frank and Wafaisade, Arasch and Lefering, Rolf and Sakka, Samir G. and Kaufmann, Jost and Heiroth, Hi-Jae and Defosse, Jerome and Böhmer, Andreas B.",
volume="28",
number="1",
pages="e21-e21",
abstract="BACKGROUND: Traumatic brain injury (TBI) is associated with high rates of long-term disability and mortality. Our aim was to investigate the effects of thoracic trauma on the in-hospital course and outcome of patients with TBI. <br><br>METHODS: We performed a matched pair analysis of the multicenter trauma database TraumaRegisterDGU® (TR-DGU) in the 5-year period from 2012 to 2016. We included adult patients (≥18 years of age) with moderate to severe TBI (abbreviated injury scale (AIS)= 3-5). Patients with isolated TBI (group 1) were compared to patients with TBI and varying degrees of additional blunt thoracic trauma (AIS<sub>Thorax</sub>= 2-5) (group 2). Matching criteria were gender, age, severity of TBI, initial GCS and presence/absence of shock. The χ<sup>2</sup>-test was used for comparing categorical variables and the Mann-Whitney-U-test was chosen for continuous parameters. Statistical significance was defined by a p-value < 0.05. <br><br>RESULTS: A total of 5414 matched pairs (10,828 patients) were included. The presence of additional thoracic injuries in patients with TBI was associated with a longer duration of mechanical ventilation and a prolonged ICU and hospital length of stay. Additional thoracic trauma was also associated with higher mortality rates. These effects were most pronounced in thoracic AIS subgroups 4 and 5. Additional thoracic trauma, regardless of its severity (AIS<sub>Thorax</sub> ≥2) was associated with significantly decreased rates of good neurologic recovery (GOS = 5) after TBI. <br><br>CONCLUSIONS: Chest trauma in general, regardless of its initial severity (AIS<sub>Thorax</sub>= 2-5), is associated with decreased chance of good neurologic recovery after TBI. Affected patients should be considered &quot;at risk&quot; and vigilance for the maintenance of optimal neuro-protective measures should be high.<p /> <p>Language: en</p>",
language="en",
issn="1757-7241",
doi="10.1186/s13049-020-0708-1",
url="http://dx.doi.org/10.1186/s13049-020-0708-1"
}