@article{ref1,
title="Ammonium dichromate poisoning",
journal="Indian journal of pediatrics",
year="2020",
author="Kumar, Himanshu and Kumar, Chandrakanta and Parmar, Kanak",
volume="ePub",
number="ePub",
pages="ePub-ePub",
abstract="Chromium (Cr) is a strong oxidant and poisoning usually begins with gastrointestinal symptoms progressing to multiorgan failure. Lethal dose of chromium salt varies between 6 to 8 g in adults [1, 2] and 1 g in children. In the human body, Cr VI is reduced to Cr III, a non-toxic form, in the plasma but when the reducing capacity is saturated, Cr VI enters the cell and causes damage by lipid peroxidation and enzyme inhibition [3].   Shortly after oral ingestion of chromates gastrointestinal mucosa is damaged, manifesting as rice-water stools, emesis, and corrosive burns of the mouth and esophagus [3]. Systemic absorption in large doses, lead to shock with multiorgan failure especially hepato-renal involvement [4, 5].<p /> <p>Language: en</p>",
language="en",
issn="0019-5456",
doi="10.1007/s12098-020-03331-x",
url="http://dx.doi.org/10.1007/s12098-020-03331-x"
}