@article{ref1,
title="Suicide and dementia: systematic review and meta-analysis",
journal="Revista de psiquiatrí́a y salud mental",
year="2020",
author="Álvarez Muñoz, Francisco Javier and Rubio-Aparicio, María and Gurillo Muñoz, Pedro and García Herrero, Ana María and Sánchez-Meca, Julio and Navarro-Mateu, Fernando",
volume="ePub",
number="ePub",
pages="ePub-ePub",
abstract="INTRODUCTION: To analyse the possible relationship between dementia in the elderly and the subsequent development of suicide ideation, attempts and / or completed suicides.   METHODS: Systematic review and meta-analysis.   SELECTION CRITERIA: studies that analysed the relationship between dementia and suicide.   SEARCH STRATEGY: i) in PubMed, EMBASE, CINAHL, IME and Lilacs until December 2018; ii) manual search of the bibliography of selected articles; iii) contact with leading authors. Article selection and data extraction according to a predefined protocol, including bias risk assessment, were performed by independent peer reviewers. The effect size index was calculated using Odds Ratio (OR) and its 95% confidence interval (random-effects model). Heterogeneity was evaluated with forest plots, Cochran's Q and I2 index. Assessment of publication bias using funnel plots (&quot;trim-and-fill&quot; method) and the Egger test. The analysis of moderating variables was performed using a multiple meta-regression under a mixed-effects model.   RESULTS: 37 studies and 47 basic units of study were identified. Effect size of the association of dementia with: Suicidal Ideation OR = 1.37 (95% CI:.78-2.39); Suicide Attempt: OR = 2.24 (95% CI: 1.01-4.97); and Completed Suicide: OR = 1.28 (95% CI:.77-2.14). Possible publication bias was ruled out.   CONCLUSIONS: A trend towards suicidal events is identified, especially suicide attempts in people with dementia. Greater attention and care are recommended after a recent diagnosis of dementia, especially with adequate assessment of comorbidities, which could influence the occurrence and outcome of suicidal events.<p /> <p>Language: en</p>",
language="en",
issn="1888-9891",
doi="10.1016/j.rpsm.2020.04.012",
url="http://dx.doi.org/10.1016/j.rpsm.2020.04.012"
}