@article{ref1,
title="Opioid poisoning",
journal="Medicine (Abingdon)",
year="2020",
author="Layne, Kerry and Wood, David M.",
volume="48",
number="3",
pages="211-213",
abstract="Opioids are among the most commonly prescribed analgesic medications, and opioid toxicity is becoming an increasing problem across the world. Patients typically present with a triad of signs: reduced consciousness, miosis and a reduced respiratory rate with shallow breaths. Patients with significant opioid toxicity are at risk of airway compromise, and basic supportive measures should be performed. Naloxone is a non-selective μ-opioid receptor antagonist that competitively binds to the μ-opioid receptor and should be administered, ideally intravenously, to patients with significant opioid toxicity.<p /> <p>Language: en</p>",
language="en",
issn="1357-3039",
doi="10.1016/j.mpmed.2019.12.018",
url="http://dx.doi.org/10.1016/j.mpmed.2019.12.018"
}