@article{ref1,
title="Alcohols and glycols poisoning",
journal="Medicine (Abingdon)",
year="2020",
author="Waring, William Stephen",
volume="48",
number="3",
pages="185-188",
abstract="Ethanol intoxication is widely encountered and can cause coma, hypotension, hypoglycaemia and acid-base disturbances. Isopropyl alcohol and its metabolite acetone cause profound depression of the central nervous system with rapid onset. Toxic alcohols include methanol, ethylene glycol and diethylene glycol; these cause severe metabolic acidosis, acute renal failure and, for methanol, severe visual disturbance. Toxicity is attributable to metabolites rather than the alcohol or glycol, and there is a characteristic delay between ingestion and severe toxicity. Management strategies include early administration of fomepizole, to minimize formation of toxic metabolites, and haemodialysis to remove metabolites in patients presenting late.<p /> <p>Language: en</p>",
language="en",
issn="1357-3039",
doi="10.1016/j.mpmed.2019.12.009",
url="http://dx.doi.org/10.1016/j.mpmed.2019.12.009"
}