@article{ref1,
title="Effect of a 1-year short message service in detoxified alcohol-dependent patients (CAPS): a multi-centre, open-label randomised controlled trial",
journal="Addiction",
year="2020",
author="Lucht, Michael and Quellmalz, Anne and Mende, Meinhard and Broda, Anja and Schmiedeknecht, Anett and Brosteanu, Oana and Höppner-Buchmann, Jacqueline and Langosch, Jens and Stuppe, Markus and Schomerus, Georg and Klauer, Thomas and Grabe, Hans J. and Freyberger, Harald J. and John, Ulrich and Meyer, Christian",
volume="ePub",
number="ePub",
pages="ePub-ePub",
abstract="BACKGROUND AND AIMS: Existing evidence suggests that text message interventions can help people reduce their alcohol consumption. However, studies with alcohol dependent patients are lacking. In this study a 1-year automatic mobile phone-based short messaging service (SMS) intervention on alcohol consumption in patients after alcohol detoxification in hospital was compared with treatment as usual.   DESIGN: Multicenter, randomized, controlled, 2 parallel-group, observer-blinded trial SETTING: Primary and secondary care: 4 hospitals and community (1 million residents, 7600 km2 area in Germany).   PARTICIPANTS: A total of 462 patients with alcohol-dependence (ICD-10) were included during inpatient detoxification treatment. Patients were randomly assigned (1:1) to an SMS intervention and treatment as usual (SMS+TAU; n=230; mean age: 45.4 years; 22.6% women) or TAU alone (n=232 mean age: 44.5 years; 22.8% women).   INTERVENTIONS: Planned, automated messages were sent to patients over 1 year to record assistance needs. A &quot;Yes&quot; or missing response triggered a phone call from a hospital therapist. Outcome was assessed by an independent survey center.   MEASUREMENTS: The primary endpoint was a 3-category alcohol consumption measure covering months 10-12 after discharge: abstinence, non-heavy drinking, heavy drinking (men >60 g/d; women >40 g/d equal to WHO criteria: high risk and very high risk, mean consumption). Secondary endpoints were number of abstinent days over 12 months and frequency of abstinence.   FINDINGS: The arms differed primarily in the heavy drinking category (intervention group 22.2%, TAU-only group 32.3%) in months 9 to 12. This is reflected by an odds ratio (OR) 1.68, 95%CI 1.11 to 2.54, p = 0.015 for heavy drinking vs. non-heavy drinking/abstinence. No difference between treatments was found with respect to any drinking vs. abstinence (OR=1.13). These results were confirmed by models adjusting for randomisation strata.   CONCLUSIONS: In Germany, a 12 month mobile phone short messaging service-based intervention enhanced the reduction in heavy drinking for 1 year in routine care among adults with alcohol dependence discharged from inpatient alcohol detoxification.<p /> <p>Language: en</p>",
language="en",
issn="0965-2140",
doi="10.1111/add.15313",
url="http://dx.doi.org/10.1111/add.15313"
}