@article{ref1,
title="Sex differences in neuromodulation treatment approaches for traumatic brain injury: a scoping review",
journal="Journal of head trauma rehabilitation",
year="2020",
author="Phillips, Angela and Sami, Sohrab and Adamson, Maheen",
volume="35",
number="6",
pages="412-429",
abstract="OBJECTIVE: Neuromodulatory brain stimulation interventions for traumatic brain injury (TBI)-related health sequelae, such as psychiatric, cognitive, and pain disorders, are on the rise. Because of disproportionate recruitment and epidemiological reporting of TBI-related research in men, there is limited understanding of TBI development, pathophysiology, and treatment intervention outcomes in women. With data suggesting sex-related variances in treatment outcomes, it is important that these gaps are addressed in emerging, neuromodulatory treatment approaches for TBI populations.   METHODS: Four research databases (PubMED, EMBASE, CINAHL, and PsycINFO) were electronically searched in February 2020.   DESIGN: This PRISMA Scoping Review (PRISMA-ScR)-guided report contextualizes the importance of reporting sex differences in TBI + neuromodulatory intervention studies and summarizes the current state of reporting sex differences when investigating 3 emerging interventions for TBI outcomes.   RESULTS: Fifty-four studies were identified for the final review including 12 controlled trials, 16 single or case series reports, and 26 empirical studies. Across all studies reviewed, 68% of participants were male, and only 7 studies reported sex differences as a part of their methodological approach, analysis, or discussion.   CONCLUSION: This review is hoped to update the TBI community on the current state of evidence in reporting sex differences across these 3 neuromodulatory treatments of post-TBI sequelae. The proposed recommendations aim to improve future research and clinical treatment of all individuals suffering from post-TBI sequelae.<p /> <p>Language: en</p>",
language="en",
issn="0885-9701",
doi="10.1097/HTR.0000000000000631",
url="http://dx.doi.org/10.1097/HTR.0000000000000631"
}