@article{ref1,
title="Polypharmacy, physical and nutritional status, and depression in the elderly: do polypharmacy deserve some credits in these problems?",
journal="Experimental aging research",
year="2020",
author="Eyigor, Sibel and Kutsal, Yeşim Gökçe and Toraman, Fusun and Durmus, Bekir and Gokkaya, Kutay Ordu and Aydeniz, Ali and Paker, Nurdan and Borman, Pinar",
volume="ePub",
number="ePub",
pages="ePub-ePub",
abstract="BACKGROUND: To investigate the association of polypharmacy with physical function, nutritional status, and depression in the elderly. <br><br>METHOD: The study included 675 people aged over 65 years from 8 centers in various geographical regions. The polypharmacy status was categorized as non-polypharmacy (0-4 drugs), polypharmacy (≥5 drugs). The subjects' physical function was assessed based on their &quot;physical activity levels, Holden ambulation scores, gait speeds, and hand grip strengths&quot;; their nutritional status based on the &quot;Mini Nutritional Assessment (MNA)&quot;; and their psychological status based on the &quot;Center for Epidemiologic Studies Depression Scale -CES-D&quot;. <br><br>RESULTS: The presence of polypharmacy in this population was found to be 30% (n = 203). A statistically significant difference was found between the groups on the level of physical activity, Holden ambulation score, and nutrition status (p < .05). There was a statistically significant difference between the groups also on hand grip strength, MNA score, Charlson score (p < .05). <br><br>CONCLUSION: Polypharmacy was observed to have a significant association with physical function, nutrition, and depression in the elderly aged ≥ 65 years.<p /> <p>Language: en</p>",
language="en",
issn="0361-073X",
doi="10.1080/0361073X.2020.1846949",
url="http://dx.doi.org/10.1080/0361073X.2020.1846949"
}