@article{ref1,
title="Are non-abstinent reductions in World Health Organization drinking risk level a  valid treatment target for alcohol use disorders in adolescents with ADHD?",
journal="Addictive behaviors reports",
year="2020",
author="Mitchell, Henry M. and Park, Grace and Hammond, Christopher J.",
volume="12",
number="",
pages="e100312-e100312",
abstract="INTRODUCTION: Abstinence from drinking represents the primary treatment target for  alcohol use disorders (AUD) in youth, but few adolescents who engage in problematic  drinking seek treatment. A reduction in World Health Organization (WHO) drinking  risk level has been established as valid and reliable non-abstinent treatment target  for AUD in adults but remains unstudied in youth. <br><br>METHODS: The present study used  data from the NIDA-CTN-0028 trial to examine associations between reductions in WHO  drinking risk level and changes in global functioning and attention-deficit  hyperactivity disorder (ADHD) symptoms during treatment in a sample of adolescents  (ages 13-18 years) with ADHD and comorbid substance use disorder (SUD) (n = 297, 61%  with AUD) receiving a 16-week intervention that combined ADHD pharmacotherapy  (OROS-methylphenidate vs. placebo) and drug-focused cognitive-behavioral therapy. <br><br>RESULTS: Shifts in drinking risk level during treatment were highly variable in  adolescents treated for ADHD/SUD, and influenced by AUD diagnostic status. In the  total sample, 15% of participants had a 2-level or greater reduction in WHO drinking  risk level, with 59% and 24% showing no change or an increase in risk-level during  treatment respectively. Achieving at least a 2-level change in WHO drinking risk  level during treatment was associated with greater reduction in ADHD symptoms and  better functional outcomes. <br><br>CONCLUSIONS: These findings parallel the adult AUD  literature and provide preliminary support for the use 2-level reductions in WHO  risk levels for alcohol use as a clinically valid non-abstinent treatment outcome  for youth with ADHD and comorbid AUD.<p /> <p>Language: en</p>",
language="en",
issn="2352-8532",
doi="10.1016/j.abrep.2020.100312",
url="http://dx.doi.org/10.1016/j.abrep.2020.100312"
}