@article{ref1,
title="Cognitive functioning in first episode psychosis. gender differences and relation  with clinical variables",
journal="Early intervention in psychiatry",
year="2020",
author="Vila-Badia, Regina and Del Cacho, Núria and Butjosa, Anna and Ochoa, Susana and Serra-Arumí, Clara and Esteban-Sanjusto, Marina and Pardo, Marta and Dolz, Montserrat and Casado-Ortega, Ariadna and Coromina, Marta and Usall, Judith",
volume="ePub",
number="ePub",
pages="ePub-ePub",
abstract="AIMS: to study the differences in cognitive functioning in patients and controls. In  addition, study the influence of symptoms, cannabis consumption, chlorpromazine  doses, DUP and IQ in cognitive performance in patients, both in the total sample and  divided by gender. <br><br>METHODS: 70 first episode psychosis patients and 63 healthy  controls (HC) participated in the study and were assessed with the MATRICS battery  and the Vocabulary subtest of WAIS-IV. Symptoms in FEP patients were evaluated with  the Emsley factors of the PANSS scale. <br><br>RESULTS: patients showed lower scores than  controls in all cognitive domains studied. There were no significant differences  between FEP men and FEP women, but we found gender differences in favour of women in  processing speed, working memory and composite total scored domains in the HC group. Finally, symptoms and Chlorpromazine doses showed an influence on cognitive  performance in the total FEP sample. When splitting the sample by gender, positive  symptoms may be more detrimental to women's cognitive functioning, while  disorganized symptoms may play the most important role in cognitive performance in  men. <br><br>CONCLUSIONS: patients showed worse cognitive performance in all cognitive  domains compared to healthy controls. In our FEP sample, gender does not seem to  influence cognitive performance measured with the MATRICS. Severity of symptoms  influences positively in cognitive performance. The dose of Chlorpromazine and  symptoms are influential variables to be taken into account in cognition  rehabilitation programs.<p /> <p>Language: en</p>",
language="en",
issn="1751-7885",
doi="10.1111/eip.13110",
url="http://dx.doi.org/10.1111/eip.13110"
}