@article{ref1,
title="Increasing risks of suicide attempt and suicidal drug overdose after head trauma in patients with sleep-disordered breathing: a population-based study",
journal="Frontiers in psychiatry",
year="2020",
author="Harnod, Dorji and Lin, Cheng-Li and Harnod, Tomor and Kao, Chia-Hung",
volume="11",
number="",
pages="e533784-e533784",
abstract="OBJECTIVE: To determine the risks of suicide attempt (SA) and suicidal drug overdose  (SDO) after head trauma in patients with sleep-disordered breathing (SDB) by using  the National Health Insurance Research Database of Taiwan. <br><br>METHODS: We analyzed the  data of patients aged ≥20 years who were diagnosed with SDB between 2000 and 2012. We further divided them into two cohorts [with admission for head injury (SBI) and  without (SBN)], and we compared them against sex-, age-, comorbidity-, and  index-date-matched healthy individuals. The adjusted hazard ratios (aHRs) and 95%  confidence intervals of SA and SDO were calculated with adjustment of age, sex, and  comorbidities. <br><br>RESULTS: Approximately 0.61% of patients among the overall 142,063  patients with SDB had SA, with 535 and 335 patients included in the SBN and SBI  cohorts, respectively. Compared with patients with SBN, a significantly higher risk  of SA was observed in patients with SBI (aHR = 2.22), especially in those aged under  50 years (aHR = 2.48). Notably, a SDO incidence of 1.20% was noted in patients with  SDB, and the SBI cohort had a 1.81-fold higher risk for SDO when compared with the  SBN cohort. <br><br>CONCLUSION: The risks of subsequent SA and SDO are proportionally  increased by the effects of head trauma with a moderating role of SDB, especially in  those aged <50 years. SDB and head trauma can increase suicide behaviors  individually and synergistically.<p /> <p>Language: en</p>",
language="en",
issn="1664-0640",
doi="10.3389/fpsyt.2020.533784",
url="http://dx.doi.org/10.3389/fpsyt.2020.533784"
}