@article{ref1,
title="Trait disinhibition and nogo event-related potentials in violent mentally disordered  offenders and healthy controls",
journal="Frontiers in psychiatry",
year="2020",
author="Delfin, Carl and Ruzich, Emily and Wallinius, Märta and Björnsdotter, Malin and Andiné, Peter",
volume="11",
number="",
pages="e577491-e577491",
abstract="Trait disinhibition may function as a dispositional liability toward maladaptive  behaviors relevant in the treatment of mentally disordered offenders (MDOs). Reduced  amplitude and prolonged latency of the NoGo N2 and P3 event-related potentials have  emerged as promising candidates for transdiagnostic, biobehavioral markers of trait  disinhibition, yet no study has specifically investigated these two components in  violent, inpatient MDOs. Here, we examined self-reported trait disinhibition,  experimentally assessed response inhibition, and NoGo N2 and P3 amplitude and  latency in male, violent MDOs (N = 27) and healthy controls (N = 20). MDOs had a  higher degree of trait disinhibition, reduced NoGo P3 amplitude, and delayed NoGo P3  latency compared to controls. The reduced NoGo P3 amplitude and delayed NoGo P3  latency in MDOs may stem from deficits during monitoring or evaluation of behavior. NoGo P3 latency was associated with increased trait disinhibition in the whole  sample, suggesting that trait disinhibition may be associated with reduced neural  efficiency during later stages of outcome monitoring or evaluation. <br><br>FINDINGS for  NoGo N2 amplitude and latency were small and non-robust. With several limitations in  mind, this is the first study to demonstrate attenuated NoGo P3 amplitude and  delayed NoGo P3 latency in violent, inpatient MDOs compared to healthy controls.<p /> <p>Language: en</p>",
language="en",
issn="1664-0640",
doi="10.3389/fpsyt.2020.577491",
url="http://dx.doi.org/10.3389/fpsyt.2020.577491"
}