@article{ref1,
title="Emotional traumatic experiences significantly contribute to identify a maltreated ecophenotype sub-group in eating disorders: experimental evidence",
journal="European eating disorders review",
year="2020",
author="Monteleone, Alessio Maria and Cascino, Giammarco and Ruzzi, Valeria and Pellegrino, Francesca and Patriciello, Giuseppina and Barone, Eugenia and Carfagno, Marco and Monteleone, Palmiero and Maj, Mario",
volume="ePub",
number="ePub",
pages="ePub-ePub",
abstract="OBJECTIVE: Eating disorders (EDs) are associated with a high prevalence of childhood maltreatment (CM). We aimed to experimentally assess if people with EDs and history  of CM show altered biological, emotional and behavioural responses to the Trier  Social Stress Test (TSST). <br><br>METHODS: According to Childhood Trauma Questionnaire  cut-off scores, 29 participants (14 with anorexia nervosa [AN] and 15 with bulimia  nervosa [BN]) were classified as maltreated (Mal) ED participants while 19  participants (11 with AN and eight with BN) without CM were identified as no  maltreated (noMal) ED participants. Cortisol, anxiety and hunger responses to TSST  and post-stress body dissatisfaction were measured. <br><br>RESULTS: Mal ED people showed  heightened emotional reactivity, lower levels of hunger and more severe post-stress  body dissatisfaction in comparison with noMal ones. Higher cortisol production was  observed in people with AN, regardless of CM history, and in those with BN and  emotional CM. Emotional trauma was the main CM type contributing to the experimental  differences observed in Mal ED people. <br><br>CONCLUSIONS: This is the first study  providing experimental and multi-level support to the maltreated ecophenoptype  hypothesis in people with EDs. These findings may promote new insights into the  biological bases of EDs and provide novel therapeutic implications.<p /> <p>Language: en</p>",
language="en",
issn="1072-4133",
doi="10.1002/erv.2818",
url="http://dx.doi.org/10.1002/erv.2818"
}