@article{ref1,
title="Childhood adversities and salivary cortisol responses to the Trier Social Stress Test: a systematic review of studies using the Children Trauma Questionnaire (CTQ)",
journal="International journal of environmental research and public health",
year="2021",
author="Lai, Chuk Ling Julian and Lee, Daryl Yu Heng and Leung, Monique On Yee",
volume="18",
number="1",
pages="e29-e29",
abstract="Alteration in cortisol response to acute social stressors has been hypothesized to mediate childhood adversities (CA) and increased morbidity in adulthood. However,  the evidence supporting an association between CA and cortisol response to social  stressors is inconclusive. The present review addressed this issue by reviewing the  literature on CA and cortisol response to acute social stressors, with a focus on  studies with adolescents or adults, using the Childhood Trauma Questionnaire (CTQ)  to assess CA, and examining salivary cortisol response to the Trier Social Stress  Test (TSST). Systematic searches of relevant articles in PsycINFO, PubMed, Web of  Science and ScienceDirect in February and March 2020 identified 12 articles  including 1196 participants with mean ages ranging from 15.3 to 52.3 yrs. across  studies. CTQ scores were significantly associated with cortisol response in 2  studies. In addition, the physical abuse and emotional neglect subscales were  associated with cortisol response respectively in 2 separate studies. The lack of  association between CA and cortisol response calls for more longitudinal studies,  and the use of formal records of maltreatment or informant reports in future  research to complement information collected by retrospective measures. In addition,  increased attention to biological mechanisms other than that associated with the  regulation of cortisol in explaining the connection between CA and psychiatry  morbidity is warranted.<p /> <p>Language: en</p>",
language="en",
issn="1661-7827",
doi="10.3390/ijerph18010029",
url="http://dx.doi.org/10.3390/ijerph18010029"
}