@article{ref1,
title="Association between antidepressant treatment during pregnancy and postpartum self-harm ideation in women with psychiatric disorders: a cross-sectional,  multinational study",
journal="International journal of environmental research and public health",
year="2021",
author="Vallee, Jennifer and Wong, Yih and Mannino, Eline and Nordeng, Hedvig and Lupattelli, Angela",
volume="18",
number="1",
pages="e46-e46",
abstract="This study sought to estimate whether there is a preventative association between antidepressants during pregnancy and postpartum self-harm ideation (SHI), as this  knowledge is to date unknown. Using the Multinational Medication Use in Pregnancy  Study, we included a sample of mothers who were in the five weeks to one year  postpartum period at the time of questionnaire completion, and reported preexisting  or new onset depression and/or anxiety during pregnancy (n = 187). Frequency of  postpartum SHI ('often/sometimes' = frequent, 'hardly ever' = sporadic, 'never') was  measured via the Edinburgh Postnatal Depression Scale (EPDS) item 10, which reads  &quot;The thought of harming myself has occurred to me&quot;. Mothers reported their  antidepressant use in pregnancy retrospectively. Overall, 52.9% of women took an  antidepressant during pregnancy. Frequent SHI postpartum was reported by 15.2% of  non-medicated women and 22.0% of women on past antidepressant treatment in  pregnancy; this proportion was higher following a single trimester treatment  compared to three trimesters (36.3% versus 18.0%). There was no preventative  association of antidepressant treatment in pregnancy on reporting frequent SHI  postpartum (weighted RR: 1.90, 95% CI: 0.79, 4.56), relative to never/hardly ever  SHI. In a population of women with antenatal depression/anxiety, there was no  preventative association between past antidepressant treatment in pregnancy and  reporting frequent SHI in the postpartum year. This analysis is only a first step in  providing evidence to inform psychiatric disorder treatment decisions for pregnant  women.<p /> <p>Language: en</p>",
language="en",
issn="1661-7827",
doi="10.3390/ijerph18010046",
url="http://dx.doi.org/10.3390/ijerph18010046"
}