
@article{ref1,
title="A proof-of-concept trial of a community-based aerobic exercise program for individuals with traumatic brain injury",
journal="Brain injury",
year="2021",
author="Ding, Kan and Tarumi, Takashi and Tomoto, Tsubasa and Bell, Kathleen R. and Madden, Christopher and Dieppa, Marisara and Cullum, C. Munro and Zhang, Song and Zhang, Rong",
volume="ePub",
number="ePub",
pages="ePub-ePub",
abstract="OBJECTIVE: To assess the feasibility of conducting an aerobic exercise training study in a community setting for individuals with traumatic brain injury (TBI)  Methods: This is a prospective, randomized, and controlled study. Nine participants  (three moderate-to-severe and six mild TBI) were randomized to a community-based  3-month individualized aerobic exercise training program (AET). Seven participants  (four moderate-to-severe, three mild TBI) were randomized to a stretching and toning  program (SAT). Cardiorespiratory fitness (CRF) level was assessed with peak oxygen  uptake (VO(2peak)) testing. <br><br>RESULTS: After 3 months of training, the AET trended  toward improved VO(2peak) when compared with the SAT group (8% vs - 4%, p = .059)  with a large effect size of 1.27. Only 50% of participants in the AET group  completed more than 70% of the assigned exercise sessions. No adverse events were  reported. Both the AET and SAT groups reported small improvements in self-reported  mood symptoms, including depression, anxiety, and anger. <br><br>CONCLUSIONS: It is feasible  to conduct an exercise training study and improve CRF for persons with TBI in  community settings with structured exercise protocols. However, exploring methods to  enhance adherence is crucial for future exercise clinical trials to improve brain  health in this population.<p /> <p>Language: en</p>",
language="en",
issn="0269-9052",
doi="10.1080/02699052.2020.1865569",
url="http://dx.doi.org/10.1080/02699052.2020.1865569"
}