@article{ref1,
title="Effectiveness of non-pharmacological falls prevention interventions for people with Multiple Sclerosis, Parkinson's Disease and stroke: protocol for an umbrella review",
journal="HRB open research",
year="2020",
author="Coote, Susan and Comber, Laura and Clifford, Amanda M. and O'Malley, Nicola",
volume="3",
number="",
pages="e17-e17",
abstract="BACKGROUND: Falls are common among people with neurological diseases and have many negative physical, psychosocial and economic consequences. Implementation of  single-diagnosis falls prevention interventions is currently problematic due to lack  of participants and resources. Given the similarities in falls risk factors across  stroke, Parkinson's Disease (PD) and Multiple Sclerosis (MS), the development of an  intervention designed for mixed neurological populations seems plausible and may  provide a pragmatic solution to current implementation challenges. This umbrella  review aims to summarise the totality of evidence regarding the effectiveness of  non-pharmacological falls prevention interventions for people with MS, PD and stroke  and identify the commonalities and differences between effective interventions for  each disease to inform the development of an evidence-based intervention that can be  tailored for people with mixed diagnoses. <br><br>METHODS: This umbrella review will be  conducted and reported in accordance with the Preferred Reporting Items for  Systematic Reviews and Meta-Analyses (PRISMA) statement. 15 electronic databases and  grey literature will be searched. Systematic reviews of randomised controlled trials  and studies investigating the effects of non-pharmacological falls prevention  interventions on falls outcomes among people with MS, PD and stroke will be  included. <br><br>METHODological quality of included reviews will be assessed using the  Assessment of Multiple Systematic Reviews 2 tool. The Grading of Recommendations  Assessments, Development and Evaluation framework will be used to rate the quality  of evidence. A summary of evidence table and narrative synthesis will be utilised to  clearly indicate the findings. <br><br>DISCUSSION: This umbrella review presents a novel and  timely approach to synthesise existing falls literature to identify effective  non-pharmacological interventions for people with MS, PD and stroke. Of importance,  a robust methodology will be used to explore the differences and similarities in  effective interventions for individuals with these neurological conditions to  facilitate the development of an intervention for these mixed neurological groups.<p /> <p>Language: en</p>",
language="en",
issn="2515-4826",
doi="10.12688/hrbopenres.13023.2",
url="http://dx.doi.org/10.12688/hrbopenres.13023.2"
}