@article{ref1,
title="Role of astrocytes in major neuropsychiatric disorders",
journal="Neurochemical research",
year="2021",
author="O'Donovan, Sinead M. and McCullumsmith, Robert E. and Wen, Zhexing and Shukla, Rammohan and Hamoud, Abdul-Rizaq A. and Alnafisah, Rawan S. and Zhang, Xiaolu",
volume="ePub",
number="ePub",
pages="ePub-ePub",
abstract="Astrocytes are the primary homeostatic cells of the central nervous system, essential for normal neuronal development and function, metabolism and response to  injury and inflammation. Here, we review postmortem studies examining changes in  astrocytes in subjects diagnosed with the neuropsychiatric disorders schizophrenia  (SCZ), major depressive disorder (MDD), and bipolar disorder (BPD). We discuss the  astrocyte-related changes described in the brain in these disorders and the  potential effects of psychotropic medication on these findings. Finally, we describe  emerging tools that can be used to study the role of astrocytes in neuropsychiatric  illness.<p /> <p>Language: en</p>",
language="en",
issn="0364-3190",
doi="10.1007/s11064-020-03212-x",
url="http://dx.doi.org/10.1007/s11064-020-03212-x"
}