@article{ref1,
title="Mechanism and prognostic indicators for explosion-related eye trauma: eye injury vitrectomy study",
journal="Acta ophthalmologica",
year="2021",
author="Ma, Zhi-zhong and Hu, Yun-Tao and Jiang, Yan-Rong and Chen, Hui-Jin and Pang, Xiu-Qin and Nie, Hong-Ping and Wang, Zhi-Jun and Yao, Yi and Feng, Kang",
volume="ePub",
number="ePub",
pages="ePub-ePub",
abstract="PURPOSE: To explore the clinical features, surgical interventions and prognosis of injured eyes following explosion and to develop the risk factors for poor prognosis. <br><br>METHODS: A nested case-control study. To the date of 31 December 2018, 99  explosion-related eye globes were selected from the Eye Injury Vitrectomy Study  database, which is a multicenter prospective cohort study and began in 1990s. All  cases selected underwent vitreoretinal surgery or enucleation and were followed up  for at least 6 months. Clinically meaningful preoperative variables and outcomes  were used to develop logistic regression models. <br><br>RESULTS: The unfavourable outcomes  were defined as silicone oil-filled eyes, phthisis bulbi, enucleation and  anatomically restored eyes whose final BCVA is worse than initial vision after  6 months of follow-up. The proportion of unfavourable outcomes was 92.0%, 60.9% and  66.7% in large festive fireworks, detonator and beer bottle groups respective. The  anatomic and visual outcome of injured eyes with combined injury of blast wave and  projectile were worse than that of ruptured eyes (Fisher's exact = 0.041). The  extrusion of iris/lens (OR = 3.20, p = 0.015), PVR-C (OR = 6.08, p = 0.036) and  choroid damage (OR = 5.84, p = 0.025) is independent risk factors of unfavourable  prognosis for explosion-related eye trauma. <br><br>CONCLUSION: The extrusion of iris/lens,  PVR-C and choroid damage is the independent risk factors for unfavourable outcomes  in explosion-related eye trauma. There is a unique injury mechanism in  explosion-related eye trauma. SUMMARY STATEMENT: Through the nested case-control  study, the extrusion of iris/lens, PVR-C, and choroid damage are the independent  risk factors for unfavorable outcomes in explosion-related eye trauma. The mechanism  of open globe mixture and close globe mixture in explosion-related eye trauma need  more cases and participating units to explore together in the future.<p /> <p>Language: en</p>",
language="en",
issn="1755-375X",
doi="10.1111/aos.14713",
url="http://dx.doi.org/10.1111/aos.14713"
}