@article{ref1,
title="Obstructive sleep apnea: a sharp increase in the prevalence of patients treated with nasal CPAP over the last decade in France",
journal="PLoS one",
year="2021",
author="Mandereau-Bruno, Laurence and Delmas, Marie-Christine and Leger, Damien",
volume="16",
number="1",
pages="e0245392-e0245392",
abstract="INTRODUCTION: Obstructive sleep apnea (OSA) is a frequent condition. In the absence of treatment, OSA is associated with a higher risk of traffic accidents and a large  variety of diseases. The objectives of this study were to describe the  characteristics of patients treated for OSA in France and assess the time trends in  treatment. <br><br>METHODS: The French National Health Data System is an individual database  with data on all healthcare reimbursements for the entire French population. Based  on this database, we included all patients aged 20 years or over who were treated  with continuous positive airway pressure (CPAP) or mandibular advancement splint  (MAS) between 2009 and 2018. Negative binomial models, adjusted for age, were used  to assess time trends in treatment prevalence and incidence rates. <br><br>RESULTS: In 2017,  2.3% of French adults aged ≥20 years were treated with CPAP (men: 3.3%; women:  1.3%). The highest prevalence was observed in people aged 70-74 years (5.0%). From  2009 to 2018, the annual prevalence of CPAP increased 3-fold and the annual  incidence 1.9-fold. During the same period, the rate of patients reimbursed for MAS  (first prescription or renewal) was multiplied by 7.6. The proportion of patients  treated with CPAP in 2017 who were no longer treated in the subsequent year was  6.9%. <br><br>DISCUSSION: The sharp increase in the incidence of OSA treatment probably  reflects a better recognition of the disease in France. However, the prevalence of  OSA treatment remains lower than expected based on the international literature. Further studies are needed to identify the obstacles to an optimal management of  individuals with OSA in France.<p /> <p>Language: en</p>",
language="en",
issn="1932-6203",
doi="10.1371/journal.pone.0245392",
url="http://dx.doi.org/10.1371/journal.pone.0245392"
}