@article{ref1,
title="Association between childhood maltreatment and symptoms of obsessive-compulsive disorder: a meta-analysis",
journal="Frontiers in psychiatry",
year="2020",
author="Ou, Wenwen and Li, Zhijun and Zheng, Qi and Chen, Wentao and Liu, Jin and Liu, Bangshan and Zhang, Yan",
volume="11",
number="",
pages="e612586-e612586",
abstract="BACKGROUND: Previous studies have indicated that childhood maltreatment (CM) may potentially influence the clinical symptomatology of obsessive-compulsive disorder (OCD). Here, we aimed to quantify the relationship between CM and obsessive-compulsive symptoms (OCS) and depressive symptoms in OCD through a meta-analysis. <br><br>METHOD: We searched PubMed, Embase, Cochrane Library, and PsycARTICLES databases for articles reporting the association between CM and OCD on April 15, 2020. Random-effect models were used to quantify the relationship between CM and the severity of OCS and depressive symptoms in OCD. <br><br>RESULTS: Ten records with 1,611 OCD patients were included in the meta-analysis. The results revealed that CM is positively correlated with the severity of OCS [r = 0.10, 95%Confidence Interval (CI): 0.01-0.19, P = 0.04] as well as depressive symptoms in OCD (r = 0.15, 95%CI: 0.07-0.24, P = 0.0002). For the subtypes of CM, childhood emotional abuse (CEA) and childhood sexual abuse (CSA) was related with the severity of OCS (r = 0.11, 95%CI: 0.03-0.19, P = 0.009) and obsession (r = 0.13, 95%CI: 0.03-0.23, P = 0.01), respectively. <br><br>CONCLUSION: Our meta-analysis indicates that OCD patients who suffered more CM may exhibit more severe OCS and depressive symptoms.<p /> <p>Language: en</p>",
language="en",
issn="1664-0640",
doi="10.3389/fpsyt.2020.612586",
url="http://dx.doi.org/10.3389/fpsyt.2020.612586"
}