@article{ref1,
title="Clinical predictors of driving simulator performance in drivers with multiple sclerosis",
journal="Multiple Sclerosis: Clinical and Laboratory Research",
year="2021",
author="Krasniuk, Sarah and Classen, Sherrilene and Morrow, Sarah A. and Alvarez, Liliana and He, Wenqing and Srinivasan, Sivaramakrishnan and Monahan, Miriam",
volume="ePub",
number="ePub",
pages="ePub-ePub",
abstract="BACKGROUND: Drivers with multiple sclerosis (MS) may experience visual-cognitive impairment that affects their fitness to drive. Due to limitations associated with the on-road assessment, an alternative assessment that measures driving performance is warranted. Whether clinical indicators of on-road outcomes can also predict driving performance outcomes on a driving simulator are not fully understood. <br><br>OBJECTIVE: This study examined if deficits in immediate verbal/auditory recall (California Verbal Learning Test-Second Edition; CVLT2-IR) and/or slower divided attention (Useful Field of View™; UFOV2) predicted deficits in operational, tactical, or strategic maneuvers assessed on a driving simulator, in drivers with and without MS. <br><br>METHODS: Participants completed the CVLT2-IR, UFOV2, and a driving simulator assessment of operational, tactical, and strategic maneuvers. <br><br>RESULTS: Deficits in immediate verbal/auditory recall and slower divided attention predicted adjustment to stimuli errors, pertaining to tactical maneuvers only, in 36 drivers with MS (vs 20 drivers without MS; F(3, 51) = 6.1, p = 0.001, R(2) = 0.3, Radj2 = 0.2). <br><br>CONCLUSION: The CVLT2-IR and UFOV2 capture the visual and verbal/auditory recall, processing speed, and divided attention required to appropriately adjust to stimuli in a simulated driving environment. Clinicians may use the CVLT2-IR and UFOV2 as precursors to driving performance deficits in drivers with MS.<p /> <p>Language: en</p>",
language="en",
issn="1352-4585",
doi="10.1177/1352458521992507",
url="http://dx.doi.org/10.1177/1352458521992507"
}