
@article{ref1,
title="The impact of hiv-related neuropsychological dysfunction on driving behavior. the hnrc group",
journal="Journal of the International Neuropsychological Society",
year="1999",
author="Marcotte, Thomas D. and Heaton, Robert K. and Wolfson, T. and Taylor, M. J. and Alhassoon, O. and Arfaa, K. and Ellis, R. J. and Grant, Igor",
volume="5",
number="7",
pages="579-592",
abstract="HIV infection often results in neuropsychological (NP) impairment. In order to assess the impact that HIV-related NP deficits may have on automobile driving, we evaluated 68 HIV-seropositive drivers using an NP battery and two PC-based driving simulations. Thirty-two participants were classified as NP impaired; most (72%) evidenced only mild impairment, and none met criteria for HIV-associated dementia. After controlling for degree of immunosuppression and disease stage, NP-impaired participants failed a previously validated driving simulation at a much higher rate than cognitively intact participants [OR = 5.3, 95% CI (1.7, 17.0), p = .006]. Similarly, on a simulation of city driving, NP impaired participants were more likely to fail based upon the number of accidents [OR = 6.1, 95% CI (1.5, 24.6), p = .01]. Simulator performance was predicted by functioning in a number of NP domains, with NP tests accounting for 13-30% of the variance on the simulations. Although it would be premature to extrapolate these findings to impairment in on-the-road driving, they do argue for greater attention to the impact that even mild HIV-related NP deficits may have on driving skills.<p /> <p>Language: en</p>",
language="en",
issn="1355-6177",
doi="",
url="http://dx.doi.org/"
}