@article{ref1,
title="Reasoning, problem solving, attention/vigilance, and working memory are candidate phenotypes of non-suicidal self-injury in Chinese Han nationality",
journal="Neuroscience letters",
year="2021",
author="Hu, Zhizhong and Yuan, Xin and Zhang, Yanyan and Lu, Zihang and Chen, Jinyuan and Hu, Maorong",
volume="ePub",
number="ePub",
pages="ePub-ePub",
abstract="BACKGROUND: Non-suicidal self-injury (NSSI) is an act of deliberately hurting one's body without the purpose of death. Internal phenotypes have been used in numerous studies of mental disorders, suicide, and self-injury. This research aimed to evaluate the cognitive function of patients with NSSI and determine their potential endophenotype. <br><br>METHODS: This study used a comparative control design and included 61 patients with NSSI, 55 healthy siblings (HS), and 53 healthy controls. Visual learning, reasoning and problem, verbal learning, attention/vigilance, working memory, and speed of processing were used to evaluate the cognitive function of the subjects. <br><br>RESULTS: Patients with NSSI and their HS showed cognitive defects in reasoning and problem, attention/vigilance, and working memory. Substantial differences were observed in verbal learning among the three groups, but no significant difference was recorded in the scores in Brief Assessment of Cognition in Schizophrenia. <br><br>CONCLUSIONS: The results suggest that reasoning and problem, attention/vigilance, and working memory may be potential endophenotypes in early identification of Chinese Han people with NSSI behavior.<p /> <p>Language: en</p>",
language="en",
issn="0304-3940",
doi="10.1016/j.neulet.2021.135878",
url="http://dx.doi.org/10.1016/j.neulet.2021.135878"
}