@article{ref1,
title="Sports related brain injury and neurodegeneration in athletes",
journal="Current molecular pharmacology",
year="2021",
author="Dhote, Vipin V. and Raja, Muthu Kumaradoss Mohan Maruga and Samundre, Prem and Sharma, Supriya and Anwikar, Shraddha and Upaganlawar, Aman B.",
volume="ePub",
number="ePub",
pages="ePub-ePub",
abstract="Sports deserve a special place in human life to impart healthy and refreshing wellbeing. However, sports activities, especially contact sports, renders athlete vulnerable to brain injuries. Athletes participating in a contact sport like boxing, rugby, American football, wrestling, and basketball are exposed to traumatic brain injuries (TBI) or concussions. The acute and chronic nature of these heterogeneous injuries provides a spectrum of dysfunctions that alters the neuronal, musculoskeletal, and behavioral responses of an athlete. Many sports-related brain injuries go unreported, but these head impacts trigger neurometabolic disruptions that contribute to long-term neuronal impairment. The pathophysiology of post-concussion and its underlying mechanisms are undergoing intense research. It also shed light on chronic disorders like Parkinson's disease, Alzheimer's disease, and dementia. In this review, we examined post-concussion neurobehavioral changes, tools for early detection of signs, and their impact on the athlete. Further, we discussed the role of nutritional supplements in ameliorating neuropsychiatric diseases in athletes.<p /> <p>Language: en</p>",
language="en",
issn="1874-4672",
doi="10.2174/1874467214666210910114324",
url="http://dx.doi.org/10.2174/1874467214666210910114324"
}