@article{ref1,
title="Aggression is more strongly associated with suicidality, independent of depression, than emotional instability and impulsivity in people with epilepsy",
journal="Epilepsy and behavior",
year="2022",
author="Lee, Sang-Ahm and Choi, Eun Ju and Jeon, Ji-Ye and Han, Su-Hyun and Kim, Hyun-Woo and Lee, Gha-Hyun and Ryu, Han Uk and Im, Kayeong and Yang, Ha-Rin",
volume="129",
number="",
pages="e108613-e108613",
abstract="PURPOSE: We evaluated the relative contributions of emotional instability, impulsivity, and aggression to the presence of suicide risk in people with epilepsy after adjusting for depressive symptoms. <br><br>METHODS: This was a cross-sectional study that used the short form of the Affective Lability Scale (ALS-18), the Barratt Impulsiveness Scale Version 11 (BIS-11), the Brief Aggression Questionnaire (BAQ), and the Patient Health Questionnaire-9 (PHQ-9). Suicidality was assessed using the Mini International Neuropsychiatric Interview (MINI), and the presence of suicide risk was defined as a MINI suicidality score ≥1. Stepwise logistic regression and mediation analyses using a two-stage regression method were performed. <br><br>RESULTS: Of the 171 subjects (63.2% men) included, suicide risk was present in 38 subjects (22.2%). The stepwise logistic regression analysis identified four variables that were independently associated with suicide risk: higher PHQ-9 score, higher BAQ score, longer duration of epilepsy, and unemployment. The univariate analysis showed that ALS-18 and BIS-11 scores were significantly associated with suicide risk; however, they were backward eliminated from the logistic model according to the criterion of p > 0.1. The mediating effects of ALS-18 and BIS-11 scores on suicide risk via PHQ-9 scores (but not BAQ scores) were significant, with the proportion mediated 61.5% and 54.0% of the total effect, respectively. <br><br>CONCLUSIONS: Alongside depressive symptoms, aggression may be a more useful concept than emotional instability and impulsivity for identifying suicidal risk in people with epilepsy.<p /> <p>Language: en</p>",
language="en",
issn="1525-5050",
doi="10.1016/j.yebeh.2022.108613",
url="http://dx.doi.org/10.1016/j.yebeh.2022.108613"
}