@article{ref1,
title="Suicide risk and lithium-reply [letter]",
journal="JAMA Psychiatry",
year="2022",
author="Katz, Ira R. and Ferguson, Ryan E. and Liang, Matthew H.",
volume="ePub",
number="ePub",
pages="ePub-ePub",
abstract="In Reply We appreciate the comments of Manchia and colleagues on our study1 on lithium treatment for prevention of repeated suicide-related outcomes in veterans with major depression or bipolar disorder. The study reported a nonsignificant hazard ratio for repeated suicide-related behaviors (ie, nonfatal suicide attempts, interrupted attempts, hospitalizations specifically to prevent suicidal behavior, and deaths by suicide) for lithium vs placebo of 1.10 (95% CI, 0.77-1.55), indicating that a treatment effect greater than 23% is unlikely. Manchia and colleagues state, &quot;The findings contrast with a bulk of naturalistic and epidemiological data showing an evident suicide-protective effect with lithium.&quot;...<p /> <p>Language: en</p>",
language="en",
issn="2168-622X",
doi="10.1001/jamapsychiatry.2022.0084",
url="http://dx.doi.org/10.1001/jamapsychiatry.2022.0084"
}