
@article{ref1,
title="Completed suicide is associated with a higher polygenic burden for psychiatric disorders",
journal="European archives of psychiatry and clinical neuroscience",
year="2022",
author="Mitjans, Marina and Papiol, Sergi and Barrot, Carme and Guardiola-Ripoll, Maria and Giménez-Palomo, Anna and Gavín, Patricia and Oraki Kohshour, Mojtaba and Acosta, Miriam and Pomarol-Clotet, Edith and Castellà-García, Josep and Pérez-Pérez, Rosa M. and Gutiérrez, Blanca and Schulze, Thomas G. and Fatjó-Vilas, Mar and Arias, Barbara and Benabarre, Antoni",
volume="ePub",
number="ePub",
pages="ePub-ePub",
abstract="Suicide is one of the most relevant public health concerns nowadays, involving approximately 1 million annual deaths worldwide. According to World Health Organization (WHO) reports, deaths due to suicide have increased by 60% in the last 50 years, and they account for 1.4% of premature deaths worldwide.   Several studies have convincingly shown that major psychiatric disorders have substantially elevated suicide mortality risks compared with the general population. Psychological autopsies of suicide completers indicate that a large fraction (87.3%) of subjects dead by suicide had been previously diagnosed with a mental disorder [1]. Along these lines, long-term follow-up studies have shown that a diagnosis of psychosis or major depression or earlier suicide attempts at baseline represent the largest risk factors for suicide mortality...<p /> <p>Language: en</p>",
language="en",
issn="0940-1334",
doi="10.1007/s00406-022-01398-5",
url="http://dx.doi.org/10.1007/s00406-022-01398-5"
}