@article{ref1,
title="Suicide risk in rheumatoid arthritis patients is associated with suboptimal vitamin D levels",
journal="Journal of clinical rheumatology",
year="2022",
author="Calderón Espinoza, Ivette and Chavarria-Avila, Efrain and Pizano-Martinez, Oscar and Martínez-García, Erika Aurora and Armendáriz-Borunda, Juan and Marquez-Aguirre, Ana Laura and Llamas-García, Arcelia and Corona-Sánchez, Esther Guadalupe and Toriz González, Guillermo and Vazquez-Del Mercado, Monica",
volume="ePub",
number="ePub",
pages="ePub-ePub",
abstract="BACKGROUND/OBJECTIVE: Rheumatoid arthritis (RA) patients might experience anxiety and depressive symptoms. Deficient vitamin D levels may be a trigger for these conditions. The aim of this study was to determine the frequency of depression, anxiety symptoms, and suicidal risk or ideation in patients with RA associated with vitamin D serum levels. <br><br>METHODS: In this cross-sectional study, we recruited RA patients older than 18 years, classified into 3 groups according to serum vitamin D levels: sufficient, ≥30 ng/mL; insufficient, 20-29 ng/mL; and deficient, <20 ng/mL. Based on the self-reported Plutchik and the Hospital Anxiety and Depression Scale, we evaluated the association of suicidal risk, depression, and anxiety with the vitamin D levels in RA and the Rheumatoid Arthritis Quality-of-Life Questionnaire. <br><br>RESULTS: We studied 72 patients with RA between January and October 2019. We found an inverse correlation between Plutchik score and suicidal risk with inadequate vitamin D levels, but not with the Hospital Anxiety and Depression Scale. Suicidal ideation was associated with a higher score on the Rheumatoid Arthritis Quality-of-Life Questionnaire. <br><br>CONCLUSIONS: Despite the high prevalence of depressive and anxiety symptoms in RA patients, a Plutchik low correlation coefficient with inadequate serum levels of vitamin D was found. However, in the analysis of covariance, we were able to find that vitamin D levels remain associated with a reduction of reduction of suicide ideation. Further studies are needed to identify a risk profile for early psychological interventions to improve the quality of life in RA patients.<p /> <p>Language: en</p>",
language="en",
issn="1076-1608",
doi="10.1097/RHU.0000000000001823",
url="http://dx.doi.org/10.1097/RHU.0000000000001823"
}