@article{ref1,
title="Prevalence and influencing factors of spinal cord injury-related osteoporosis and fragility fractures in Thai people with chronic spinal cord injury: a cross-sectional, observational study",
journal="Journal of spinal cord medicine",
year="2022",
author="Mahitthiharn, Kanyanat and Kovindha, Apichana and Kaewchur, Tawikar and Morse, Leslie R. and Pattanakuhar, Sintip",
volume="ePub",
number="ePub",
pages="ePub-ePub",
abstract="OBJECTIVE: To investigate the prevalence and influencing factors of spinal cord injury (SCI)-related osteoporosis and fragility fractures in Thai people with chronic spinal cord injury. <br><br>DESIGN: A cross-sectional, observational study. SETTING: Outpatient clinic, Department of Rehabilitation Medicine, Maharaj Nakorn Chiang Mai Hospital. PARTICIPANTS: Thais with chronic spinal cord injury (SCI) (duration of injury at least one year). INTERVENTION: Not applicable. OUTCOME MEASURES: Dual-energy X-ray absorptiometry (DXA) was performed to measure bone mineral density (BMD) at the hip. Analyses were performed to identify risk factors for SCI-related osteoporosis or fragility fracture development. Thai FRAX® score was calculated with and without BMD and compared for each participant. <br><br>RESULTS: Among 64 Thais with chronic SCI, the prevalence of SCI-related osteoporosis was 43.8%. Female sex, non-ambulatory status, and at least 10 years duration of spinal cord injury increased the risk of having SCI-related osteoporosis. The prevalence of fragility fracture was 9.4%. Female sex, duration of SCI, and being diagnosed with SCI-related osteoporosis increased the risk of having a fragility fracture. Thai FRAX® score without BMD value underestimated the risk of prevalent fracture in 7.8% of participants. <br><br>CONCLUSIONS: SCI-related osteoporosis and fragility fractures are common in Thais with chronic SCI. Our findings emphasize the importance of SCI-related osteoporosis and fragility fracture surveillance in people with chronic SCI regardless of their ethnicity. FRAX® without BMD calculations could underestimate the risk of fragility fracture in people with chronic SCI. Therefore, further studies are needed to develop an SCI-specific fracture-risk assessment tool using risk factors proposed in previous studies and in this study.<p /> <p>Language: en</p>",
language="en",
issn="1079-0268",
doi="10.1080/10790268.2022.2054763",
url="http://dx.doi.org/10.1080/10790268.2022.2054763"
}