@article{ref1,
title="A rare case of a chemical burn: dithranol with salicylic acid",
journal="World journal of plastic surgery",
year="2022",
author="Selva Raj, Dharshanan Raj and Adjei, Bismark and Al-Nahhas, Omar Farooq and Kamil, Lutfi and Yonjan, Indira",
volume="11",
number="1",
pages="138-140",
abstract="A 16-year-old female with psoriasis presented to our Plastic Surgery Department with a significant chemical burn to the neck, upper torso and left cheek (TBSA 6%). She applied a concoction of cream prescribed by her dermatologist in her native country, Poland when she returned to the United Kingdom. A few hours after application she developed a burn with pH of 5. A review of the cream revealed a mixture of 19% dithranol and 5% salicylic acid. This combination is recognized for managing psoriasis, however the strength of dithranol in the combination given is of a high concentration (normally <3%). This alone can cause a burn to the skin if left for a prolonged period of time. Salicylic acid is an enhancer which augments the stability of dithranol and increases its penetration and efficacy. The concentration of 5% is also on the higher end. Our patient was admitted for pain relief and further irrigation till normalization of the pH which was achieved after 3 days. A worrying aspect in our patients' case is that she was given the cream to commence at home. High concentration preparation is normally commenced in a controlled setting under medical supervision.<p /> <p>Language: en</p>",
language="en",
issn="2228-7914",
doi="10.52547/wjps.11.1.138",
url="http://dx.doi.org/10.52547/wjps.11.1.138"
}