@article{ref1,
title="A pilot randomized controlled trial of docosahexaenoic acid for the treatment of sport-related concussion in adolescents",
journal="Clinical pediatrics",
year="2022",
author="Miller, Shane M. and Zynda, Aaron J. and Sabatino, Meagan J. and Jo, Chanhee and Ellis, Henry B. and Dimeff, Robert J.",
volume="ePub",
number="ePub",
pages="ePub-ePub",
abstract="The objective was to examine the use of docosahexaenoic acid (DHA) for the treatment of sport-related concussion (SRC) in adolescent athletes. We hypothesize that participants who intake 2 g of DHA daily will not experience differences in recovery compared with participants who take a placebo. This double-blind, randomized controlled pilot trial was performed in a tertiary pediatric sports medicine clinic from 2013 to 2017 in adolescents (14-18 years) presenting with diagnosed SRC within 4 days of injury. Forty participants were randomized into DHA or PLACEBO group and were instructed to take 2 capsules twice daily for 12 weeks. Participants in the DHA group were symptom-free earlier than the PLACEBO group (11.0 vs 16.0 days, P =.08) and were cleared to begin the Return to Sport progression (14.0 vs 19.5 days, P =.12) sooner. The use of 2 g/day of DHA was well-tolerated and did not significantly affect recovery times in adolescent athletes following SRC.  Clinical Trial Registration: ClincalTrials.gov, NCT01903525.<p /> <p>Language: en</p>",
language="en",
issn="0009-9228",
doi="10.1177/00099228221101726",
url="http://dx.doi.org/10.1177/00099228221101726"
}