@article{ref1,
title="Baseline health-related quality of life predicts falls: a secondary analysis of a randomized controlled trial",
journal="Quality of life research",
year="2022",
author="Davis, Jennifer C. and Hsu, Chun Liang and Ghag, Cheyenne and Starkey, Samantha Y. and Jacova, Patrizio and Dian, Larry and Parmar, Naaz and Madden, Kenneth and Liu-Ambrose, Teresa",
volume="ePub",
number="ePub",
pages="ePub-ePub",
abstract="PURPOSE: Among older adults, health-related quality of life (HRQoL) and falls are associated. Generic patient-reported outcomes measures (PROMs) assess individual's HRQoL. The role for PROMs, a potential tool for predicting subsequent falls, remains under-explored. Our primary aim was to determine whether a baseline PROMs assessment of HRQoL may be a useful tool for predicting future falls. <br><br>METHODS: A secondary analysis of a 12-month randomized clinical trial (RCT) of a home-based exercise program among 344 adults (67% female), aged ≥ 70 years, with ≥ 1 falls in the prior year who were randomized (1:1) to either a home-based exercise program (n = 172) or usual care (n = 172). A negative binomial regression model with total falls count as the dependent variable evaluated the main effect of the independent variable-baseline HRQoL (measured by the Short-Form-6D)-controlling for total exposure time and experiment group (i.e., exercise or usual care) for the total sample. For the usual care group alone, the model controlled for total exposure time. <br><br>RESULTS: For the total sample, the rate of subsequent total falls was significantly predicted by baseline HRQoL (IRR = 0.044; 95% CI [0.005-0.037]; p = .004). For the usual care group, findings were confirmed with wider confidence intervals and the rate of prospective total falls was significantly predicted by baseline HRQoL (IRR = 0.025; 95% CI [0.001-0.909]; p = .044). <br><br>CONCLUSION: These findings suggest the ShortForm-6D should be considered as part of falls prevention screening strategies within a Falls Prevention Clinic setting.   Trial Registrations ClinicalTrials.gov Protocol Registration System. Identifier: NCT01029171; URL: https://clinicaltrials.gov/ct2/show/NCT01029171. Identifier: NCT00323596; URL: https://clinicaltrials.gov/ct2/show/NCT00323596.<p /> <p>Language: en</p>",
language="en",
issn="0962-9343",
doi="10.1007/s11136-022-03175-2",
url="http://dx.doi.org/10.1007/s11136-022-03175-2"
}