@article{ref1,
title="Increased risk of suicidality in patients with psoriasis: a nationwide cohort study in Korea",
journal="Journal of the European Academy of Dermatology and Venereology",
year="2022",
author="Kim, S. M. and Ahn, J. and Cho, Y. A. and Sung, J. Y. and Kim, C. Y. and Yu, D. and Lee, Y. W. and Won, S. and Choe, Y. B.",
volume="ePub",
number="ePub",
pages="ePub-ePub",
abstract="BACKGROUND: Psoriasis has a devastating psychological impact on patients' quality of life. However, the relationship between suicidality and psoriasis remains unclear. <br><br>OBJECTIVE: This study analyzed and compared the risk of suicidality (suicidal ideation, suicide attempt, and completed suicide) between patients with psoriasis and the general population. <br><br>METHODS: This nationwide, population-based, retrospective, cohort study analyzed the Korean National Health Insurance Service claim data from 2005 to 2018. <br><br>RESULTS: The study included 348,439 patients with psoriasis aged over 18 years and with age- and sex-matched controls. The risk of suicidality was higher in the psoriasis group than in the control group (adjusted hazard ratio [aHR] 1.21; 95% confidence interval [CI], 1.18-1.24). The aHR of suicidality was higher in the psoriatic arthritis group (aHR, 1.46; 95% CI, 1.39-1.54) than in the psoriasis-alone group (aHR, 1.17; 95% CI, 1.13-1.20). However, the severity of psoriasis and suicidality showed no correlation (mild psoriasis group: aHR, 1.22; 95% CI, 1.18-1.25; moderate-to-severe psoriasis group: aHR, 1.16; 95% CI, 1.10-1.23). <br><br>CONCLUSION: Patients with psoriasis have an increased risk of suicidality. In particular, the presence of arthritis in patients had a more significant effect on the risk of suicidality.<p /> <p>Language: en</p>",
language="en",
issn="0926-9959",
doi="10.1111/jdv.18565",
url="http://dx.doi.org/10.1111/jdv.18565"
}