@article{ref1,
title="The characteristics of withdrawal or withholding of life-sustaining treatment in severe traumatic brain injury: a single Japanese institutional study",
journal="World neurosurgery: X",
year="2023",
author="Tanizaki, Shinsuke and Toma, Yasuo and Miyashita, Katsuyoshi and Maeda, Shigenobu",
volume="17",
number="",
pages="e100144-e100144",
abstract="OBJECTIVES: There is little evidence on the factors influencing the decision to withdraw or continue life-sustaining treatment in the setting of severe traumatic brain injury in Japanese institutions. We investigated the factors associated with the withdrawal or withholding of life-sustaining treatment (WLST) for severe traumatic brain injury at a single Japanese institution. <br><br>METHODS: A total of 161 patients with severe traumatic brain injury were retrospectively reviewed. Patient characteristics and injury types were compared between patients with and without the WLST. <br><br>RESULTS: Of the 161 patients, 87 (54%) died and 52 (32%) decided to undergo WLST. In 98% of the WLST cases, the decision was made within 24 h of admission. The mean duration between WLST and death was 2 days. The predicted probabilities for mortality and unfavorable outcomes were highest in patients with WLST within 24 h. Patients with WLST were older and had a higher frequency of falls on the ground, ischemic heart disease, and acute subdural hemorrhage than those without WLST. <br><br>CONCLUSIONS: The decisions of almost all WLST cases were made within 24 h of admission for severe traumatic brain injury in a Japanese institution because of Japanese patients' religious and cultural backgrounds.<p /> <p>Language: en</p>",
language="en",
issn="2590-1397",
doi="10.1016/j.wnsx.2022.100144",
url="http://dx.doi.org/10.1016/j.wnsx.2022.100144"
}