@article{ref1,
title="Depression and cognitive sequelae after a traumatic brain lesion",
journal="Danish medical journal",
year="2022",
author="Ryttersgaard, Trine Okkerstrøm and Riis, Jens Østergaard and Johnsen, Søren Paaske and Mogensen, Poul Henning and Bjarkam, Carsten Reidies",
volume="70",
number="1",
pages="A02220108-A02220108",
abstract="INTRODUCTION: To improve rehabilitation in young people with an acquired brain injury, the Danish Ministry of Health initiated the &quot;National study on young brain injury survivors&quot; in 2012. Using data from this initiative, we examined the changes in depression, cognition, global functional outcome and return to work/school among young traumatic brain injury (TBI) survivors. <br><br>METHOD: This was an observational one-year follow-up study based on data from &quot;Danish registry for young adults with acquired brain injury&quot;. The main measures were Major Depression Inventory, neuropsychological examination, and Glasgow Outcome Scale - extended (GOS-E). <br><br>RESULTS: A total of 76 young TBI survivors attended two interdisciplinary examinations and had complete data. Sixty-six (86.8%) had rehabilitation between the two visits, and the global functional outcome was vastly higher at the second visit (z = -3.373, p = 0.0007). At the first versus the second visit, the prevalence proportion of depression was 14.5% (95% confidence interval (CI): 7.5-24.4) versus 10.5% (95% CI: 4.7-19.7), and for cognitive sequelae it was 31.6% (95% CI: 21.4-43.3) versus 19.7% (95% CI: 11.5-30.5). Patients with depression and/or cognitive sequelae had a lower GOS-E score (p = 0.0016) than patients without depression/cognitive sequelae and a negative association was found between depression, cognitive sequelae and return to work/school (p = 0.045). <br><br>CONCLUSION: Emotional and cognitive rehabilitation for young TBI survivors seems essential as depression and cognitive sequelae are associated with a lower global functional outcome and return to work/school.   FUNDING: none.   TRIAL REGISTRATION: not relevant.<p /> <p>Language: en</p>",
language="en",
issn="2245-1919",
doi="",
url="http://dx.doi.org/"
}