@article{ref1,
title="Sex differences in health conditions associated with sexual assault in a large hospital population",
journal="Complex Psychiatry",
year="2023",
author="Lake, Allison M. and Goleva, Slavina B. and Samuels, Lauren R. and Carpenter, Laura M. and Davis, Lea K.",
volume="8",
number="3-4",
pages="80-89",
abstract="INTRODUCTION: Sexual assault is an urgent public health concern with both immediate and long-lasting health consequences, affecting 44% of women and 25% of men during their lifetimes. Large studies are needed to understand the unique healthcare needs of this patient population. <br><br>METHODS: We mined clinical notes to identify patients with a history of sexual assault in the electronic health record (EHR) at Vanderbilt University Medical Center (VUMC), a large university hospital in the Southeastern USA, from 1989 to 2021 (N = 3,376,424). Using a phenome-wide case-control study, we identified diagnoses co-occurring with disclosures of sexual assault. We performed interaction tests to examine whether sex modified any of these associations. Association analyses were restricted to a subset of patients receiving regular care at VUMC (N = 833,185). <br><br>RESULTS: The phenotyping approach identified 14,496 individuals (0.43%) across the VUMC-EHR with documentation of sexual assault and achieved a positive predictive value of 93.0% (95% confidence interval = 85.6-97.0%), determined by manual patient chart review. Out of 1,703 clinical diagnoses tested across all subgroup analyses, 465 were associated with sexual assault. Sex-by-trauma interaction analysis revealed 55 sex-differential associations and demonstrated increased odds of psychiatric diagnoses in male survivors. <br><br>DISCUSSION: This case-control study identified associations between disclosures of sexual assault and hundreds of health conditions, many of which demonstrated sex-differential effects. The findings of this study suggest that patients who have experienced sexual assault are at risk for developing wide-ranging medical and psychiatric comorbidities and that male survivors may be particularly vulnerable to developing mental illness.<p /> <p>Language: en</p>",
language="en",
issn="2673-3005",
doi="10.1159/000527363",
url="http://dx.doi.org/10.1159/000527363"
}