@article{ref1,
title="Epidemiology of mental health comorbidity in patients with psoriasis: an analysis of trends from 1986 to 2019",
journal="Psychiatry research",
year="2023",
author="Liu, Liu and Lin, Nai-Xuan and Yu, Yuan-Ting and Wang, Si-Han and Wang, Jiao and Cai, Xiao-Ce and Wang, Chun-Xiao and Zhang, Miao and Li, Xin and Li, Bin",
volume="321",
number="",
pages="e115078-e115078",
abstract="BACKGROUND: The prevalence of mental disorders such as depression, anxiety, and suicide has increased in patients with psoriasis, although no study has systematically analyzed the epidemiology worldwide. <br><br>OBJECTIVE: To explore the prevalence and incidence of psoriasis with comorbid mental disorders (i.e., depression, anxiety, and suicide). <br><br>METHODS: Five databases from establishment through May 2022 were searched. Stata SE 15.1 was used for the data analysis. Subgroup, meta-regression, and sensitivity analyses were used to evaluate the heterogeneity of pooled studies. <br><br>RESULTS: We evaluated 56 studies in our research. The prevalence of depression, anxiety, and suicide in adults with psoriasis was 20%, 21%, and 0.77%. Patients with psoriasis in North America had a higher prevalence of depression and suicide, whereas those in South America had a higher prevalence of anxiety. The incidence of depression, anxiety, and suicide was 42.1, 24.7, and 2.6 per 1000 person-years in adults with psoriasis, respectively.   LIMITATIONS: All of the included studies were published in Chinese and English, causing a degree of selection bias. <br><br>CONCLUSION: These findings demonstrate the incidence and prevalence of comorbid mental disorders in patients with psoriasis, which may raise awareness among physicians and patients regarding the mental problems associated with psoriasis.<p /> <p>Language: en</p>",
language="en",
issn="0165-1781",
doi="10.1016/j.psychres.2023.115078",
url="http://dx.doi.org/10.1016/j.psychres.2023.115078"
}