@article{ref1,
title="Fit for purpose of on-the-road driving and simulated driving: a randomised crossover study using the effect of sleep deprivation",
journal="PLoS one",
year="2023",
author="Koopmans, Ingrid and Doll, Robert-Jan and van der Wall, Hein and de Kam, Marieke and Groeneveld, Geert Jan and Cohen, Adam and Zuiker, Rob",
volume="18",
number="2",
pages="e0278300-e0278300",
abstract="INTRODUCTION: Drivers should be aware of possible impairing effects of alcohol, medicinal substance, or fatigue on driving performance. Such effects are assessed in clinical trials, including a driving task or related psychomotor tasks. However, a choice between predicting tasks must be made. Here, we compare driving performance with on-the-road driving, simulator driving, and psychomotor tasks using the effect of sleep deprivation. <br><br>METHOD: This two-way cross over study included 24 healthy men with a minimum driving experience of 3000km per year. Psychomotor tasks, simulated driving, and on-the-road driving were assessed in the morning and the afternoon after a well-rested night and in the morning after a sleep-deprived night. Driving behaviour was examined by calculating the Standard Deviation of Lateral Position (SDLP). <br><br>RESULTS: SDLP increased after sleep deprivation for simulated (10cm, 95%CI:6.7-13.3) and on-the-road driving (2.8cm, 95%CI:1.9-3.7). The psychomotor test battery detected effects of sleep deprivation in almost all tasks. Correlation between on-the-road tests and simulator SDLP after a well-rested night (0.63, p <.001) was not present after a night of sleep deprivation (0.31, p =.18). Regarding the effect of sleep deprivation on the psychomotor test battery, only adaptive tracking correlated with the SDLP of the driving simulator (-0.50, p =.02). Other significant correlations were related to subjective VAS scores. <br><br>DISCUSSION: The lack of apparent correlations and difference in sensitivity of performance of the psychomotor tasks, simulated driving and, on-the-road driving indicates that the tasks may not be interchangeable and may assess different aspects of driving behaviour.<p /> <p>Language: en</p>",
language="en",
issn="1932-6203",
doi="10.1371/journal.pone.0278300",
url="http://dx.doi.org/10.1371/journal.pone.0278300"
}