@article{ref1,
title="Characteristics of the cervical spine and cervical cord injuries in older adults with cervical ossification of the posterior longitudinal ligament",
journal="Scientific reports",
year="2023",
author="Okuwaki, Shun and Funayama, Toru and Koda, Masao and Eto, Fumihiko and Yamaji, Akihiro and Yokogawa, Noriaki and Sasagawa, Takeshi and Ando, Kei and Nakashima, Hiroaki and Segi, Naoki and Watanabe, Kota and Nori, Satoshi and Takeda, Kazuki and Furuya, Takeo and Yunde, Atsushi and Nakajima, Hideaki and Yamada, Tomohiro and Hasegawa, Tomohiko and Terashima, Yoshinori and Hirota, Ryosuke and Suzuki, Hidenori and Imajo, Yasuaki and Ikegami, Shota and Uehara, Masashi and Tonomura, Hitoshi and Sakata, Munehiro and Hashimoto, Ko and Onoda, Yoshito and Kawaguchi, Kenichi and Haruta, Yohei and Suzuki, Nobuyuki and Kato, Kenji and Uei, Hiroshi and Sawada, Hirokatsu and Nakanishi, Kazuo and Misaki, Kosuke and Terai, Hidetomi and Tamai, Koji and Shirasawa, Eiki and Inoue, Gen and Kakutani, Kenichiro and Kakiuchi, Yuji and Kiyasu, Katsuhito and Tominaga, Hiroyuki and Tokumoto, Hiroto and Iizuka, Yoichi and Takasawa, Eiji and Akeda, Koji and Takegami, Norihiko and Funao, Haruki and Oshima, Yasushi and Kaito, Takashi and Sakai, Daisuke and Yoshii, Toshitaka and Ohba, Tetsuro and Otsuki, Bungo and Seki, Shoji and Miyazaki, Masashi and Ishihara, Masayuki and Okada, Seiji and Imagama, Shiro and Kato, Satoshi",
volume="13",
number="1",
pages="e2689-e2689",
abstract="Although the incidence of cervical spinal cord injury (CSCI) with ossification of the posterior longitudinal ligament (OPLL) has increased in older adults, its etiology and neurological outcomes remain unknown. We identified OPLL characteristics and determined whether they influence neurological severity and improvement of CSCI in older patients. This multicenter retrospective cohort study identified 1512 patients aged ≥ 65 years diagnosed with CSCI on admission during 2010-2020. We analyzed CSCI etiology in OPLL patients. We performed propensity score-adjusted analyses to compare neurological outcomes between patients with and without OPLL. Cases were matched based on variables influencing neurological prognosis. The primary neurological outcome was rated according to the American Spine Injury Association (ASIA) impairment scale (AIS) and ASIA motor score (AMS). In 332 OPLL patients, the male-to-female ratio was approximately 4:1. Half of all patients displayed low-energy trauma-induced injury and one-third had CSCI without a bony injury. Propensity score matching created 279 pairs. There was no significant difference in the AIS grade and AMS between patients with and without OPLL during hospitalization, 6 months, and 12 months following injury. OPLL patients tended to exhibit worse neurological findings during injury; nevertheless, OPLL was not associated with poor neurological improvement in older CSCI patients.<p /> <p>Language: en</p>",
language="en",
issn="2045-2322",
doi="10.1038/s41598-023-29877-2",
url="http://dx.doi.org/10.1038/s41598-023-29877-2"
}