@article{ref1,
title="Psychomotor performances relevant for driving under the combined effect of ethanol and synthetic cannabinoids: a systematic review",
journal="Frontiers in psychiatry",
year="2023",
author="Giorgetti, Arianna and Orazietti, Vasco and Busardò, Francesco Paolo and Giorgetti, Raffaele",
volume="14",
number="",
pages="e1131335-e1131335",
abstract="OBJECTIVE: To determine whether the acute co-consumption of ethanol and synthetic cannabinoids (SCs) increases the risk of a motor vehicle collision and affects the psychomotor performances relevant for driving. <br><br>DESIGN: Systematic review of the literature. DATA SOURCES: Electronic searches were performed in two databases, unrestricted by year, with previously set method and criteria. Search, inclusion and data extraction were performed by two blind authors. <br><br>RESULTS: Twenty articles were included, amounting to 31 cases of SCs-ethanol co-consumption. The impairment of psychomotor functions varied widely between studies, ranging from no reported disabilities to severe unconsciousness. Overall, a dose-effect relationship could not be observed. <br><br>CONCLUSION: Despite the biases and limitations of the literature studies, it seems likely that the co-consumption poses an increased risk for driving. The drugs might exert a synergistic effect on the central nervous system depression, as well as on aggressiveness and mood alterations. However, more research is needed on the topic.  Keywords: Ethanol impaired driving; Drug impaired driving; Cannabis impaired driving  <p /> <p>Language: en</p>",
language="en",
issn="1664-0640",
doi="10.3389/fpsyt.2023.1131335",
url="http://dx.doi.org/10.3389/fpsyt.2023.1131335"
}