@article{ref1,
title="Exercise-induced vision dysfunction early after sport-related concussion is associated with persistent postconcussive symptoms",
journal="Clinical journal of sport medicine",
year="2023",
author="Vernau, Brian T. and Haider, Mohammad N. and Fleming, Alexander and Leddy, John J. and Willer, Barry S. and Storey, Eileen P. and Grady, Matthew F. and Mannix, Rebekah and Meehan, William and Master, Christina L.",
volume="ePub",
number="ePub",
pages="ePub-ePub",
abstract="OBJECTIVE: The purpose of this study was to determine if exercise-induced vision dysfunction [reduced performance and/or symptom exacerbation on a post-exercise King-Devick (KD) test] in adolescents early after sport-related concussion was associated with increased risk of persistent post-concussive symptoms (PPCS, recovery >28 days). We used exercise as a provocative maneuver before the KD test, hypothesizing that concussed adolescents with exercise-induced vision dysfunction would be more likely to develop PPCS. <br><br>DESIGN: Secondary analysis of data from a multi-center, randomized clinical trial comparing KD test performance before and after the Buffalo Concussion Treadmill Test in adolescents within 10 days of sport-related concussion who were randomized to aerobic exercise or placebo stretching program. SETTING: Three university-associated sports medicine clinical programs. PARTICIPANTS: Ninety-nine adolescents with sport-related concussion (exercise group: n = 50, 15.3 ± 1 years, 60% M, 22% with PPCS; stretching group: n = 49, 15.9 ± 1 years, 65% M, 35% with PPCS) tested a mean of 6 ± 2 days from injury. INDEPENDENT VARIABLE: King-Devick test performed immediately before and 2 minutes after Buffalo Concussion Treadmill Test. MAIN OUTCOME MEASURE: Persistent post-concussive symptoms. <br><br>RESULTS: Adolescents who demonstrated exercise-induced vision dysfunction upon initial evaluation developed PPCS at a significantly greater rate when compared with adolescents who did not (71% vs 34%, P < 0.001). Exercise-induced vision dysfunction corresponded to a relative risk of 3.13 for PPCS. <br><br>CONCLUSIONS: Adolescents with exercise-induced vision dysfunction had a 3-fold greater relative risk of developing PPCS than those without exercise-induced vision dysfunction.<p /> <p>Language: en</p>",
language="en",
issn="1050-642X",
doi="10.1097/JSM.0000000000001145",
url="http://dx.doi.org/10.1097/JSM.0000000000001145"
}