@article{ref1,
title="Comparing indices of responsiveness for the Coma Near-Coma Scale with and without pain items: an exploratory study",
journal="Brain and behavior",
year="2023",
author="Weaver, Jennifer A. and Pertsovskaya, Vera and Tran, Jasmine and Kozlowski, Allan J. and Guernon, Ann and Bender Pape, Theresa and Mallinson, Trudy",
volume="ePub",
number="ePub",
pages="ePub-ePub",
abstract="INTRODUCTION: This study aimed to establish the indices of responsiveness for the Coma/Near-Coma (CNC) scale without (8 items) and with (10 items) pain test stimuli. A secondary purpose was to examine whether the CNC 8 items and 10 items differ when detecting change in neurobehavioral function. <br><br>METHODS: We analyzed CNC data from three studies of participants with disorders of consciousness: one observational study and two intervention studies. We generated Rasch person measures using the CNC 8 items and CNC 10 items for each participant at two time points 14 ± 2 days apart using Rasch Measurement Theory. We calculated the distribution-based minimal clinically important difference (MCID) and minimal detectable change using 95% confidence intervals (MDC(95) ). <br><br>RESULTS: We used the Rasch transformed equal-interval scale person measures in logits. For the CNC 8 items: Distribution-based MCID 0.33 SD = 0.41 logits and MDC(95)  = 1.25 logits. For the CNC 10 items: Distribution-based MCID 0.33 SD = 0.37 logits and MDC(95) = 1.03 logits. Twelve and 13 participants made a change beyond measurement error (MDC(95) ) using the CNC 8-item and 10-item scales, respectively. <br><br>CONCLUSION: Our preliminary evidence supports the clinical and research utility of the CNC 8-item scale for measuring the responsiveness of neurobehavioral function, and that it demonstrates comparable responsiveness to the CNC 10-item scale without administering the two pain items. The distribution-based MCID can be used to evaluate group-level changes while the MDC(95) can support clinical, data-driven decisions about an individual patient.<p /> <p>Language: en</p>",
language="en",
issn="2162-3279",
doi="10.1002/brb3.3120",
url="http://dx.doi.org/10.1002/brb3.3120"
}