@article{ref1,
title="Recent advances of drugs monitoring in oral fluid and comparison with blood",
journal="Clinical chemistry and laboratory medicine",
year="2023",
author="Casati, Sara and Binda, Maddalena and Dongiovanni, Paola and Meroni, Marica and D'Amato, Alfonsina and Roda, Gabriella and Orioli, Marica and Fabbro, Massimo Del and Tartaglia, Gianluca M.",
volume="ePub",
number="ePub",
pages="ePub-ePub",
abstract="The use of alternative matrices in toxicological analyses has been on the rise in clinical and forensic settings. Oral fluid (OF), as non-invasive fluid, has attracted attention in the field of drug screening, both for therapeutic and forensic purposes, as well as for medical diagnosis, clinical management, on-site (real time) doping and for monitoring environmental exposure to toxic substances. A good correlation between OF and blood is now established for drug concentrations. Therefore, OF might be a potential substitute of blood, especially for long-term surveillance (e.g., therapeutic drugs) or to screen a large number of patients, as well as for the development of salivary point-of-care technologies. In this review, we aimed to summarize and critically evaluate the current literature that focused on the comparison of drugs detection in OF and blood specimens.<p /> <p>Language: en</p>",
language="en",
issn="1434-6621",
doi="10.1515/cclm-2023-0343",
url="http://dx.doi.org/10.1515/cclm-2023-0343"
}