@article{ref1,
title="Locomotive syndrome and depressive symptoms: a cross-sectional study in middle-aged women",
journal="Modern rheumatology",
year="2023",
author="Kato, Michitaka and Ozaki, Etsuko and Matsui, Daisuke and Nakano, Wataru and Nakano, Satoko and Ono, Sintaro and Kito, Kazuya and Koyama, Teruhide",
volume="ePub",
number="ePub",
pages="ePub-ePub",
abstract="OBJECTIVE: Evidence for an association between locomotive syndrome (LS) and depression is lacking in middle-aged women. This study aimed to investigate the relationship between LS severity and depressive symptoms in community-dwelling middle-aged women. <br><br>METHODS: This cross-sectional study included 1,520 middle-aged women (mean age 52 ± 6 years). LS severity was evaluated using the 25-question Geriatric Locomotive Function Scale (GLFS-25) questionnaire and motor function test. Depressive symptoms were assessed using the Zung self-rating depression scale (SDS). Multiple logistic regression analyses were performed to determine the association between depressive symptoms and LS severity, adjusting for potential confounding factors. <br><br>RESULTS: LS severity, as evaluated through both questionnaires and motor function tests, was significantly associated with depressive symptoms (SDS ≥ 40 points) in middle-aged women. The relationship between LS and depressive symptoms was only significant when assessed through the GLFS-25 questionnaire rather than the motor function tests. Additionally, a stepwise association was observed between pain severity, as assessed by the GLFS-25, and the prevalence of depressive symptoms. <br><br>CONCLUSIONS: LS severity is significantly associated with depressive symptoms in community-dwelling middle-aged women, suggesting the need for additional mental status assessment in participants with LS and concurrent pain.<p /> <p>Language: en</p>",
language="en",
issn="1439-7595",
doi="10.1093/mr/road096",
url="http://dx.doi.org/10.1093/mr/road096"
}