@article{ref1,
title="Mild traumatic brain injuries and risk for affective and behavioral disorders",
journal="Pediatrics",
year="2024",
author="Delmonico, Richard L. and Tucker, Lue-Yen and Theodore, Brian R. and Camicia, Michelle and Filanosky, Charles and Haarbauer-Krupa, Juliet",
volume="ePub",
number="ePub",
pages="ePub-ePub",
abstract="OBJECTIVES: Recent studies document an association between mild traumatic brain injuries (mTBIs) in children and postinjury psychiatric disorders. However. these studies were subject to limitations in the design, lack of long-term follow-up, and poorly defined psychiatric outcomes. This study determines the incidence and relative risk of postinjury new affective and behavior disorders 4 years after mTBIs. <br><br>METHODS: A cohort study of mTBI cases and matched comparisons within an integrated health care system. The mTBI group included patients ≤17 years of age, diagnosed with mTBI from 2000 to 2014 (N = 18 917). Comparisons included 2 unexposed patients (N = 37 834) per each mTBI-exposed patient, randomly selected and matched for age, sex, race/ethnicity, and date of medical visit (reference date to mTBI injury). Outcomes included a diagnosis of affective or behavioral disorders in the 4 years after mTBI or the reference date. <br><br>RESULTS: Adjusted risks for affective disorders were significantly higher across the first 3 years after injury for the mTBI group, especially during the second year, with a 34% increase in risk. Adjusted risks for behavioral disorders were significant at years 2 and 4, with up to a 37% increase in risk. The age group with the highest risk for postinjury affective and behavioral disorders was 10- to 13-year-old patients. <br><br>CONCLUSIONS: Sustaining an mTBI significantly increased the risks of having a new affective or behavioral disorder up to 4 years after injury. Initial and ongoing screening for affective and behavior disorders following an mTBI can identify persistent conditions that may pose barriers to recovery.<p /> <p>Language: en</p>",
language="en",
issn="0031-4005",
doi="10.1542/peds.2023-062340",
url="http://dx.doi.org/10.1542/peds.2023-062340"
}