@article{ref1,
title="Cannabis-related disorders and toxic effects",
journal="New England journal of medicine",
year="2024",
author="Hassouneh, Ala' and Tambyraja, Andrew L.",
volume="390",
number="9",
pages="e867-e867",
abstract="To the Editor: The review by Gorelick (Dec. 14 issue)1 regarding cannabis-related disorders highlights many of the toxic sequelae associated with the misuse of this substance. In addition, cannabis use may cause a distinct inflammatory arteritis affecting the small and medium-sized peripheral arteries in a clinical pattern similar to that seen in tobacco-associated thromboangiitis obliterans.2 More commonly, cannabis use is associated with an increased risk of premature atherosclerotic peripheral vascular disease.3 Distinguishing between these two cannabis-related arteriopathies is clinically challenging, and considerable overlap is most likely. The proposed mechanisms of cannabis-related arteriopathy are underpinned by arteritis, vasospasm, and platelet aggregation. . . .<p /> <p>Language: en</p>",
language="en",
issn="0028-4793",
doi="10.1056/NEJMc2400805",
url="http://dx.doi.org/10.1056/NEJMc2400805"
}