@article{ref1,
title="Randomized controlled trial of two internet-based written therapies for World Trade Center workers and survivors with persistent PTSD symptoms",
journal="Psychiatry research",
year="2024",
author="Feder, Adriana and Kowalchyk, Mary L. and Brinkman, Hannah R. and Cahn, Leah and Aaronson, Cindy J. and Böttche, Maria and Presseau, Candice and Fred-Torres, Sharely and Markowitz, John C. and Litz, Brett T. and Yehuda, Rachel and Knaevelsrud, Christine and Pietrzak, Robert H.",
volume="336",
number="",
pages="e115885-e115885",
abstract="Posttraumatic stress disorder (PTSD) remains prevalent among individuals exposed to the 9/11 World Trade Center (WTC) terrorist attacks. The present study compared an Internet-based, therapist-assisted psychotherapy for PTSD to an active control intervention in WTC survivors and recovery workers with WTC-related PTSD symptoms (n = 105; 75% syndromal PTSD). Participants were randomized to integrative testimonial therapy (ITT), focused on WTC-related trauma, or modified present-centered therapy (I-MPCT), each comprising 11 assigned written narratives. The primary outcome was baseline-to-post-treatment change in PTSD symptoms on the PTSD Checklist for DSM-5 (PCL-5). Secondary measures included PTSD symptom clusters, depressive/anxiety symptoms, functioning, and quality of life. A significant main effect of time was observed for the primary outcome (average &quot;large&quot; effect size improvement, d = 1.49). Significant and &quot;moderate-to-large&quot; main effects of time were also observed for all PTSD symptom clusters, depressive symptoms, quality of life, and mental health-related functioning (d range=0.62-1.33). Treatment and treatment-by-time interactions were not significant. In planned secondary analyses incorporating 3-month follow-up measures, ITT was associated with significantly greater reductions than I-MPCT in PTSD avoidance and negative alterations in cognitions and mood, anxiety, and mental health-related functioning. Both therapies significantly lowered PTSD symptoms, suggesting they may benefit hard-to-reach individuals with chronic WTC-related PTSD symptoms.<p /> <p>Language: en</p>",
language="en",
issn="0165-1781",
doi="10.1016/j.psychres.2024.115885",
url="http://dx.doi.org/10.1016/j.psychres.2024.115885"
}