@article{ref1,
title="Multi-organ involvement caused by Scedosporium apiospermum infection after near drowning: a case report and literature review",
journal="BMC neurology",
year="2024",
author="Yao, Yao and Xu, Qian and Liang, Wenwen and Ji, Suqiong and Kosari, Mohammadreza and Xu, Shabei and Zhu, Zhou and Mao, Zhijuan",
volume="24",
number="1",
pages="e124-e124",
abstract="BACKGROUND: Scedosporium apiospermum (S. apiospermum) is a rare fungal pathogen that causes disseminated infections. It rarely affects immunocompetent individuals and has a poor prognosis. CASE PRESENTATION: A 37-year-old woman presented with multiple lesions in the lungs, brain, and eyes, shortly after near drowning in a car accident. The primary symptoms were chest tightness, limb weakness, headache, and poor vision in the left eye. S. apiospermum infection was confirmed by metagenomic next-generation sequencing (mNGS) of intracranial abscess drainage fluid, although intracranial metastases were initially considered. After systemic treatment with voriconazole, her symptoms improved significantly; however, she lost vision in her left eye due to delayed diagnosis. <br><br>CONCLUSION: While S. apiospermum infection is rare, it should be considered even in immunocompetent patients. Prompt diagnosis and treatment are essential. Voriconazole may be an effective treatment option.<p /> <p>Language: en</p>",
language="en",
issn="1471-2377",
doi="10.1186/s12883-024-03637-9",
url="http://dx.doi.org/10.1186/s12883-024-03637-9"
}